Nicotine Vaping Linked to Lower Vascular Function in Young Adults
Young adults who vape nicotine daily but never smoked show lower vascular function and cardiorespiratory fitness than those who use neither product.Summary
A cross-sectional study published in JAMA Cardiology found that young adults who vape nicotine daily but have never smoked cigarettes had lower vascular function and cardiorespiratory fitness compared with peers who use neither product. The single-center study included 58 participants aged about 26 years, divided into three groups: exclusive nicotine vape users, combustible cigarette smokers, and tobacco- and nicotine-vape-naive individuals. Mean flow-mediated dilation (FMD) was 5.5% in vapers and 4.4% in smokers, versus 8.3% in the naive group, and carotid artery reactivity showed a similar pattern. Peak oxygen uptake was lower in vapers than in naive individuals but did not differ significantly between smokers and naive participants. The authors noted that FMD impairments with vaping were similar to those seen with combustible cigarettes and called for longitudinal studies to determine long-term clinical implications, cautioning that the small, cross-sectional design cannot prove causation. The findings arrive amid a shifting regulatory landscape, including FDA authorization of certain fruit-flavored electronic nicotine delivery systems, and support pharmacists reinforcing that people who do not use tobacco should not start.
(Source：Google News)
